檳榔鹼

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檳榔鹼是一種天然存在的精神活性生物鹼,是南亞和東南亞特有的檳榔(檳榔)的檳榔(檳榔)[1]

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Areca catechu - Köhler–s Medizinal-Pflanzen-014.jpg

Yu Jei Liu et al.2016 The pharmacology, toxicology and potential applications of arecoline: a review

Hsi Feng Tu et al.(2019) Arecoline‐regulated ataxia telangiectasia mutated expression level in oral cancer progression

Zhizhong Xu et al (2019)Arecoline attenuates memory impairment and demyelination in a cuprizone-induced mouse model of schizophrenia

Tian Z-H, Weng J-T, Shih L-J, Siao A-C, Chan T-Y, Tsuei Y-W, et al. (2018) Arecoline inhibits the growth of 3T3-L1 preadipocytes via AMP-activated protein kinase and reactive oxygen species pathways. PLoS ONE 13(7): e0200508. https://doi.org/10.1371/journal.pone.0200508

Ling HY, He J, Yang SS, Zhang KF, He JQ, Zhu ZM, Feng SD. [The effects of arecoline on the lipid metabolism of 3T3-L1 adipocytes]. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2017 Jan 8;33(1):22-25. doi: 10.12047/j.cjap.5448.2017.005. PMID: 29926602.

Yang B, Fu MF, Tang ZG. Hua Xi Kou Qiang Yi Xue Za Zhi. 2019;37(3):260-264. doi:10.7518/hxkq.2019.03.006 槟榔碱及机械刺激构建大鼠口腔黏膜下纤维化模型

Pan H, Li Y, Huang L, Zhou X, Lu Y, Shi F.2018 Development and validation of a rapid LC-MS/MS method for simultaneous quantification of arecoline and its two active metabolites in rat plasma and its application to a pharmacokinetic study.[J Pharm Biomed Anal.] ;154:397-403. doi: 10.1016/j.jpba.2018.03.033. Epub 2018 Mar 16. PMID: 29573735

Metformin[編輯]

Li WD, Zang CJ, Yin S, Shen W, Sun QY, Zhao M.(2020) Metformin protects against mouse oocyte apoptosis defects induced by arecoline. Cell Prolif. 2020;53(7):e12809. doi:10.1111/cpr.12809 PDF

  1. Volgin AD, Bashirzade A, Amstislavskaya TG, Yakovlev OA, Demin KA, Ho YJ, Wang D, Shevyrin VA, Yan D, Tang Z, Wang J, Wang M, Alpyshov ET, Serikuly N, Wappler-Guzzetta EA, Lakstygal AM, Kalueff AV. DARK Classics in Chemical Neuroscience: Arecoline. ACS Chem Neurosci. 2019 May 15;10(5):2176-2185. doi: 10.1021/acschemneuro.8b00711. Epub 2019 Feb 21. PMID: 30664352.